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One current examine from Yale University discovered that vanillin — an extract of the vanilla bean — transforms into chemical substances known as acetals when aerosolized. Those chemicals, the researchers said, could additionally be particularly irritating to the lungs and trigger injury when inhaled. Studies have shown that breathing in aerosolized propylene glycol may contribute to asthma. And a 2012 case report involved a lady who developed a condition known as exogenous lipoid pneumonia after vaping for about six months.